Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and synovial hyperplasia leading to progressive joint destruction. Fibroblast-like synoviocytes (FLS) are central components of the aggressive, tumour-like synovial structure termed pannus, which invades the joi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Nielsen, Natasja, Pascal, Veronique, Fasth, Andreas E R, Sundström, Yvonne, Galsgaard, Elisabeth D, Ahern, David, Andersen, Martin, Baslund, Bo, Bartels, Else M, Bliddal, Henning, Feldmann, Marc, Malmström, Vivianne, Berg, Louise, Spee, Pieter, Söderström, Kalle
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Blackwell Science Inc 2014
Θέματα:
Original Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107668/
https://ncbi.nlm.nih.gov/pubmed/24673109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12271
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