Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and synovial hyperplasia leading to progressive joint destruction. Fibroblast-like synoviocytes (FLS) are central components of the aggressive, tumour-like synovial structure termed pannus, which invades the joi...

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Hlavní autoři: Nielsen, Natasja, Pascal, Veronique, Fasth, Andreas E R, Sundström, Yvonne, Galsgaard, Elisabeth D, Ahern, David, Andersen, Martin, Baslund, Bo, Bartels, Else M, Bliddal, Henning, Feldmann, Marc, Malmström, Vivianne, Berg, Louise, Spee, Pieter, Söderström, Kalle
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2014
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107668/
https://ncbi.nlm.nih.gov/pubmed/24673109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12271
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