Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and synovial hyperplasia leading to progressive joint destruction. Fibroblast-like synoviocytes (FLS) are central components of the aggressive, tumour-like synovial structure termed pannus, which invades the joi...

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Detalhes bibliográficos
Main Authors: Nielsen, Natasja, Pascal, Veronique, Fasth, Andreas E R, Sundström, Yvonne, Galsgaard, Elisabeth D, Ahern, David, Andersen, Martin, Baslund, Bo, Bartels, Else M, Bliddal, Henning, Feldmann, Marc, Malmström, Vivianne, Berg, Louise, Spee, Pieter, Söderström, Kalle
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107668/
https://ncbi.nlm.nih.gov/pubmed/24673109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12271
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