Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and synovial hyperplasia leading to progressive joint destruction. Fibroblast-like synoviocytes (FLS) are central components of the aggressive, tumour-like synovial structure termed pannus, which invades the joi...

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Bibliografiske detaljer
Main Authors: Nielsen, Natasja, Pascal, Veronique, Fasth, Andreas E R, Sundström, Yvonne, Galsgaard, Elisabeth D, Ahern, David, Andersen, Martin, Baslund, Bo, Bartels, Else M, Bliddal, Henning, Feldmann, Marc, Malmström, Vivianne, Berg, Louise, Spee, Pieter, Söderström, Kalle
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2014
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107668/
https://ncbi.nlm.nih.gov/pubmed/24673109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12271
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