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Real time detection of cytotoxic lymphocyte function reveals distinct patterns of caspase activation mediated by Fas versus granzyme B
Activation of caspase-mediated apoptosis is reported to be a hallmark of both granzyme B- and Fas- mediated pathways of killing by cytotoxic T lymphocytes (CTL); however, the kinetics of caspase activation remain undefined due to an inability to monitor target cell-specific apoptosis in real time. W...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107314/ https://ncbi.nlm.nih.gov/pubmed/24928990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301668 |
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