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EFFECTS OF A NOVEL ORALLY ADMINISTERED CALPAIN INHIBITOR SNJ-1945 ON IMMUNOMODULATION AND NEURODEGENERATION IN A MURINE MODEL OF MULTIPLE SCLEROSIS
Multiple Sclerosis (MS) pathology is marked by the massive infiltration of myelin-specific T cells into the central nervous system (CNS). Hallmarks of T helper (Th) cells during active disease are pro-inflammatory Th1/Th17 cells that predominate over immunoregulatory Th2/Treg cells. Neurodegeneratio...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107076/ https://ncbi.nlm.nih.gov/pubmed/24447070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12659 |
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