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Calpain Inhibitor SNJ-1945 Attenuates Events Prior to Angiogenesis in Cultured Human Retinal Endothelial Cells

PURPOSE: Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis and microvascular permeability. VEGF-induced cytoskeletal reorganization plays a crucial role in angiogenesis. Cytoskeletal organization in endothelial cells is regulated by calpain proteases (EC 3.4.22.17)....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ma, Hong, Tochigi, Ayumi, Shearer, Thomas R., Azuma, Mitsuyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958445/
https://ncbi.nlm.nih.gov/pubmed/19857102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2009.0030
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