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The Involvement of Calpain in CD4(+) T Helper Cell Bias in Multple Sclerosis
The pathogenesis of multiple sclerosis (MS) is mediated by massive infiltration of myelin-specific T cells into the central nervous system (CNS). Self-reactive CD4(+) T helper (Th) cells, specifically Th1 and Th17 cells, are hallmarks of active disease in progression, whereas Th2 cells are predomina...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972924/ https://ncbi.nlm.nih.gov/pubmed/24707444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000153 |
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