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Calpain Inhibition Reduces Structural and Functional Impairment of Retinal Ganglion Cells in Experimental Optic Neuritis

Optic neuritis (ON), inflammation of the optic nerve, is strongly associated with multiple sclerosis (MS). ON pathology is characterized by attack of autoreactive T cells against optic nerve antigens, resulting in demyelination, death of retinal ganglion cells (RGCs) and cumulative visual impairment...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Smith, Amena W., Rohrer, Baerbel, Wheless, Lee, Samantaray, Supriti, Ray, Swapan K., Inoue, Jun, Azuma, Mitsuyoshi, Banik, Naren L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056830/
https://ncbi.nlm.nih.gov/pubmed/27513991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13770
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