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Calpain Inhibition Reduces Structural and Functional Impairment of Retinal Ganglion Cells in Experimental Optic Neuritis

Optic neuritis (ON), inflammation of the optic nerve, is strongly associated with multiple sclerosis (MS). ON pathology is characterized by attack of autoreactive T cells against optic nerve antigens, resulting in demyelination, death of retinal ganglion cells (RGCs) and cumulative visual impairment...

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Detalles Bibliográficos
Publicado en:J Neurochem
Autores principales: Smith, Amena W., Rohrer, Baerbel, Wheless, Lee, Samantaray, Supriti, Ray, Swapan K., Inoue, Jun, Azuma, Mitsuyoshi, Banik, Naren L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056830/
https://ncbi.nlm.nih.gov/pubmed/27513991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13770
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