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The Caspase-8 Homolog Dredd Cleaves Imd and Relish but Is Not Inhibited by p35
In Drosophila, the Imd pathway is activated by diaminopimelic acid-type peptidoglycan and triggers the humoral innate immune response, including the robust induction of antimicrobial peptide gene expression. Imd and Relish, two essential components of this pathway, are both endoproteolytically cleav...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106325/ https://ncbi.nlm.nih.gov/pubmed/24891502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544841 |
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