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kep1 interacts genetically with dredd/Caspase-8, and kep1 mutants alter the balance of dredd isoforms

The Drosophila kep1 gene encodes an RNA binding protein related to the murine QUAKING apoptotic inducer. We have previously shown that kep1 can induce apoptosis when transfected into different cell lines. To better define the role of Kep1 in apoptosis, we generated kep1 null flies. These flies were...

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Detalhes bibliográficos
Main Authors: Di Fruscio, Marco, Styhler, Sylvia, Wikholm, Eva, Boulanger, Marie-Chloé, Lasko, Paul, Richard, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149916/
https://ncbi.nlm.nih.gov/pubmed/12563030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236048100
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