Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling

Caspases have been extensively studied as critical initiators and executioners of cell death pathways. However, caspases also take part in non-apoptotic signalling events such as the regulation of innate immunity and activation of nuclear factor-κB (NF-κB). How caspases are activated under these con...

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Autores principales: Meinander, Annika, Runchel, Christopher, Tenev, Tencho, Chen, Li, Kim, Chan-Hee, Ribeiro, Paulo S, Broemer, Meike, Leulier, Francois, Zvelebil, Marketa, Silverman, Neal, Meier, Pascal
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380211/
https://ncbi.nlm.nih.gov/pubmed/22549468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.121
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