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The Caspase-8 Homolog Dredd Cleaves Imd and Relish but Is Not Inhibited by p35

In Drosophila, the Imd pathway is activated by diaminopimelic acid-type peptidoglycan and triggers the humoral innate immune response, including the robust induction of antimicrobial peptide gene expression. Imd and Relish, two essential components of this pathway, are both endoproteolytically cleav...

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Auteurs principaux: Kim, Chan-Hee, Paik, Donggi, Rus, Florentina, Silverman, Neal
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106325/
https://ncbi.nlm.nih.gov/pubmed/24891502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544841
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