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The Caspase-8 Homolog Dredd Cleaves Imd and Relish but Is Not Inhibited by p35

In Drosophila, the Imd pathway is activated by diaminopimelic acid-type peptidoglycan and triggers the humoral innate immune response, including the robust induction of antimicrobial peptide gene expression. Imd and Relish, two essential components of this pathway, are both endoproteolytically cleav...

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Библиографические подробности
Главные авторы: Kim, Chan-Hee, Paik, Donggi, Rus, Florentina, Silverman, Neal
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106325/
https://ncbi.nlm.nih.gov/pubmed/24891502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544841
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