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Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling
Caspases have been extensively studied as critical initiators and executioners of cell death pathways. However, caspases also take part in non-apoptotic signalling events such as the regulation of innate immunity and activation of nuclear factor-κB (NF-κB). How caspases are activated under these con...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380211/ https://ncbi.nlm.nih.gov/pubmed/22549468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.121 |
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