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Mouse Models for Studying the Formation and Propagation of Prions
Prions are self-propagating protein conformers that cause a variety of neurodegenerative disorders in humans and animals. Mouse models have played key roles in deciphering the biology of prions and in assessing candidate therapeutics. The development of transgenic mice that form prions spontaneously...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106304/ https://ncbi.nlm.nih.gov/pubmed/24860095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.550707 |
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