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Mouse Models for Studying the Formation and Propagation of Prions

Prions are self-propagating protein conformers that cause a variety of neurodegenerative disorders in humans and animals. Mouse models have played key roles in deciphering the biology of prions and in assessing candidate therapeutics. The development of transgenic mice that form prions spontaneously...

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Detalhes bibliográficos
Main Authors: Watts, Joel C., Prusiner, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106304/
https://ncbi.nlm.nih.gov/pubmed/24860095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.550707
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