Targeting NPM1 represents a rationale strategy for radiosensitization

PURPOSE: To test the hypothesis that small molecule targeting of nucleophosmin (NPM1) represents a rational approach for radiosensitization. METHODS AND MATERIALS: Wild type and NPM1-deficient mouse embryo fibroblasts (MEFs) were used to determine if radiosensitization produced by the small molecule...

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Detalhes bibliográficos
Main Authors: Sekhar, Konjeti R., Benamar, Mouadh, Venkateswaran, Amudhan, Sasi, Soumya, Penthala, Narsimha R, Crooks, Peter A, Hann, Stephen R, Geng, Ling, Balusu, Ramesh, Abbas, Tarek, Freeman, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105849/
https://ncbi.nlm.nih.gov/pubmed/25035215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2014.04.012
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