A Peptide of Heparin Cofactor II Inhibits Endotoxin-Mediated Shock and Invasive Pseudomonas aeruginosa Infection

Sepsis and septic shock remain important medical problems with high mortality rates. Today's treatment is based mainly on using antibiotics to target the bacteria, without addressing the systemic inflammatory response, which is a major contributor to mortality in sepsis. Therefore, novel treatm...

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Главные авторы: Kalle, Martina, Papareddy, Praveen, Kasetty, Gopinath, van der Plas, Mariena J. A., Mörgelin, Matthias, Malmsten, Martin, Schmidtchen, Artur
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105479/
https://ncbi.nlm.nih.gov/pubmed/25047075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102577
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