Structure-Activity Studies and Therapeutic Potential of Host Defense Peptides of Human Thrombin

Peptides of the C-terminal region of human thrombin are released upon proteolysis and identified in human wounds. In this study, we wanted to investigate minimal determinants, as well as structural features, governing the antimicrobial and immunomodulating activity of this peptide region. Sequential...

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Hlavní autoři: Kasetty, Gopinath, Papareddy, Praveen, Kalle, Martina, Rydengård, Victoria, Mörgelin, Matthias, Albiger, Barbara, Malmsten, Martin, Schmidtchen, Artur
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
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Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101415/
https://ncbi.nlm.nih.gov/pubmed/21402837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01515-10
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