Structure-Activity Studies and Therapeutic Potential of Host Defense Peptides of Human Thrombin

Peptides of the C-terminal region of human thrombin are released upon proteolysis and identified in human wounds. In this study, we wanted to investigate minimal determinants, as well as structural features, governing the antimicrobial and immunomodulating activity of this peptide region. Sequential...

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Detalhes bibliográficos
Main Authors: Kasetty, Gopinath, Papareddy, Praveen, Kalle, Martina, Rydengård, Victoria, Mörgelin, Matthias, Albiger, Barbara, Malmsten, Martin, Schmidtchen, Artur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101415/
https://ncbi.nlm.nih.gov/pubmed/21402837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01515-10
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