C-terminal Peptides of Tissue Factor Pathway Inhibitor Are Novel Host Defense Molecules

Tissue factor pathway inhibitor (TFPI) inhibits tissue factor-induced coagulation, but may, via its C terminus, also modulate cell surface, heparin, and lipopolysaccharide interactions as well as participate in growth inhibition. Here we show that C-terminal TFPI peptide sequences are antimicrobial...

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Bibliographic Details
Main Authors: Papareddy, Praveen, Kalle, Martina, Kasetty, Gopinath, Mörgelin, Matthias, Rydengård, Victoria, Albiger, Barbara, Lundqvist, Katarina, Malmsten, Martin, Schmidtchen, Artur
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934703/
https://ncbi.nlm.nih.gov/pubmed/20592020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127019
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