Structure-Activity Studies and Therapeutic Potential of Host Defense Peptides of Human Thrombin

Peptides of the C-terminal region of human thrombin are released upon proteolysis and identified in human wounds. In this study, we wanted to investigate minimal determinants, as well as structural features, governing the antimicrobial and immunomodulating activity of this peptide region. Sequential...

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Huvudupphovsmän: Kasetty, Gopinath, Papareddy, Praveen, Kalle, Martina, Rydengård, Victoria, Mörgelin, Matthias, Albiger, Barbara, Malmsten, Martin, Schmidtchen, Artur
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2011
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Mechanisms of Action: Physiological Effects
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101415/
https://ncbi.nlm.nih.gov/pubmed/21402837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01515-10
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