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Efficient transduction of myeloid cells by a lentiviral vector that packages the Vpx accessory protein

Lentiviral vectors are widely used for the stable expression of genes and shRNA-mediated knockdown and are currently under development for clinical use in gene therapy. Pseudotyping of the vectors with VSV-G allows them to infect a wide range of cell-types. However, myeloid cells, such as dendritic...

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Detalhes bibliográficos
Main Authors: Bobadilla, Susanne, Sunseri, Nicole, Landau, Nathaniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105013/
https://ncbi.nlm.nih.gov/pubmed/22895508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.61
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