The Determination of Importance of Sequences Neighboring the Psi Sequence in Lentiviral Vector Transduction and Packaging Efficiency

A number of lentiviral vector systems have been developed for gene delivery and therapy by eliminating and/or modifying viral genetic elements. However, all lentiviral vector systems derived from HIV-1 must have a viral packaging signal sequence, Psi (Ψ), which is placed downstream of 5′ long termin...

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Bibliographic Details
Main Authors: Kim, Seon Hee, Jun, Hyun Jeong, Jang, Soo In, You, Ji Chang
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503997/
https://ncbi.nlm.nih.gov/pubmed/23185560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050148
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