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Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork
PURPOSE: To determine if proteasome inhibition using MG132 increased the efficiency of FIV vector–mediated transduction in human trabecular meshwork (TM)-1 cells and monkey organ-cultured anterior segments (MOCAS). METHODS: TM-1 cells were pretreated for 1 hour with 0.5% dimethyl sulfoxide (DMSO; ve...
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Udgivet i: | Invest Ophthalmol Vis Sci |
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Main Authors: | , , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
The Association for Research in Vision and Ophthalmology
2018
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5961099/ https://ncbi.nlm.nih.gov/pubmed/29340644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22074 |
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