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Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice
The over-expression of NF-κB signalling in both muscle and immune cells contribute to the pathology in dystrophic muscle. The anti-inflammatory properties of glucocorticoids, mediated predominantly through monomeric glucocorticoid receptor inhibition of transcription factors such as NF-κB (transrepr...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104819/ https://ncbi.nlm.nih.gov/pubmed/23794417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4231 |
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