Contribution of Adenylyl Cyclase Modulation of Pre- and Postsynaptic GABA Neurotransmission to Morphine Antinociception and Tolerance

Opioid inhibition of presynaptic GABA release in the ventrolateral periaqueductal gray (vlPAG) activates the descending antinociception pathway. Tolerance to repeated opioid administration is associated with upregulation of adenylyl cyclase activity. The objective of these studies was to test the hy...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Bobeck, Erin N, Chen, QiLiang, Morgan, Michael M, Ingram, Susan L
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104331/
https://ncbi.nlm.nih.gov/pubmed/24622471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.62
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы