Loading...

Lack of antinociceptive cross-tolerance with co-administration of morphine and fentanyl into the periaqueductal gray of male Sprague-Dawley rats

Tolerance to the antinociceptive effect of mu-opioid receptor (MOPr) agonists, such as morphine and fentanyl, greatly limits their effectiveness for long-term use to treat pain. Clinical studies have shown that combination therapy and opioid rotation can be used to enhance opioid-induced antinocicep...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Pain
Main Authors: Bobeck, Erin N, Schoo, Shauna M, Ingram, Susan L, Morgan, Michael M
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732057/
https://ncbi.nlm.nih.gov/pubmed/30853505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2019.03.002
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!