Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model

RATIONALE: Yes-Associated Protein (YAP), the terminal effector of the Hippo signaling pathway, is crucial for regulating embryonic cardiomyocyte (CM) proliferation. OBJECTIVE: We hypothesized that YAP activation after myocardial infarction would preserve cardiac function and improve survival. METHOD...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Zhiqiang, von Gise, Alexander, Zhou, Pingzhu, Gu, Fei, Ma, Qing, Jiang, Jiangming, Yau, Allan L., Buck, Jessica N., Gouin, Katryna A., van Gorp, Pim R. R., Zhou, Bin, Chen, Jinghai, Seidman, Jonathan G., Wang, Da-zhi, Pu, William T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104149/
https://ncbi.nlm.nih.gov/pubmed/24833660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.303632
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