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Generation and Characterization of a JAK2V617F-Containing Erythroleukemia Cell Line
The JAK2V617F mutation is found in the majority of patients with myeloproliferative neoplasms (MPNs). Transgenic expression of the mutant gene causes MPN-like phenotypes in mice. We have produced JAK2V617F mice with p53 null background. Some of these mice developed acute erythroleukemia. From one of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103785/ https://ncbi.nlm.nih.gov/pubmed/25036984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099017 |
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