Transgenic expression of JAK2(V617F) causes myeloproliferative disorders in mice

The JAK2(V617F) mutation was found in most patients with myeloproliferative disorders (MPDs), including polycythemia vera, essential thrombocythemia, and primary myelofibrosis. We have generated transgenic mice expressing the mutated enzyme in the hematopoietic system driven by a vav gene promoter....

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xing, Shu, Wanting, Tina Ho, Zhao, Wanming, Ma, Junfeng, Wang, Shaofeng, Xu, Xuesong, Li, Qingshan, Fu, Xueqi, Xu, Mingjiang, Zhao, Zhizhuang Joe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2008
Gaiak:
Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384138/
https://ncbi.nlm.nih.gov/pubmed/18334677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-091579
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