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JAK2V617F and p53 mutations coexist in erythroleukemia and megakaryoblastic leukemic cell lines
BACKGROUND: JAK2V617F, a gain-of-function mutant form of tyrosine kinase JAK2, is found in the majority of patients with Ph- myeloproliferative neoplasms (MPNs), a group of chronic hematological diseases that often lead to acute leukemia. The current study is intended to find other gene mutations th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514099/ https://ncbi.nlm.nih.gov/pubmed/23210734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-1-15 |
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