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Characterization of a Highly Effective Protein Substrate for Analysis of JAK2(V617F) Activity

OBJECTIVE: Identification of JAK2(V617F) in myeloproliferative disorders makes JAK2 an important marker for disease diagnosis and a highly attractive target for therapeutic drug development. This study is intended to identify a sensitive and specific substrate for assays of the JAK2 enzymatic activi...

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Detalhes bibliográficos
Main Authors: Li, Zhe, Xing, Shu, Wang, Shaofeng, Ho, Wanting Tina, Zhao, Zhizhuang Joe
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128699/
https://ncbi.nlm.nih.gov/pubmed/17764811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2007.07.003
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