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Interaction of Ricin and Shiga Toxins with Ribosomes
Ricin and Shiga toxins designated as ribosome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate a specific adenine (A(4324) in rat 28S rRNA) in the conserved α-sarcin/ricin loop of the large rRNA, inhibiting protein synthesis. Evidence obtained from a number of studies suggests tha...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103753/ https://ncbi.nlm.nih.gov/pubmed/21910078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2011_174 |
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