Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs

Bloom syndrome is a rare autosomal recessive disorder characterized by genetic instability and cancer predisposition, and caused by mutations in the gene encoding the Bloom syndrome, RecQ helicase-like (BLM) protein. To determine whether altered gene expression might be responsible for pathological...

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Detalhes bibliográficos
Main Authors: Nguyen, Giang Huong, Tang, Weiliang, Robles, Ana I., Beyer, Richard P., Gray, Lucas T., Welsh, Judith A., Schetter, Aaron J., Kumamoto, Kensuke, Wang, Xin Wei, Hickson, Ian D., Maizels, Nancy, Monnat, Raymond J., Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103369/
https://ncbi.nlm.nih.gov/pubmed/24958861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404807111
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