Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs

Bloom syndrome is a rare autosomal recessive disorder characterized by genetic instability and cancer predisposition, and caused by mutations in the gene encoding the Bloom syndrome, RecQ helicase-like (BLM) protein. To determine whether altered gene expression might be responsible for pathological...

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Detaylı Bibliyografya
Asıl Yazarlar: Nguyen, Giang Huong, Tang, Weiliang, Robles, Ana I., Beyer, Richard P., Gray, Lucas T., Welsh, Judith A., Schetter, Aaron J., Kumamoto, Kensuke, Wang, Xin Wei, Hickson, Ian D., Maizels, Nancy, Monnat, Raymond J., Harris, Curtis C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103369/
https://ncbi.nlm.nih.gov/pubmed/24958861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404807111
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