A Novel Na(v)1.7 Mutation Producing Carbamazepine-Responsive Erythromelalgia

OBJECTIVE: Human and animal studies have shown that Na(v)1.7 sodium channels, which are preferentially expressed within nociceptors and sympathetic neurons, play a major role in inflammatory and neuropathic pain. Inherited erythromelalgia (IEM) has been linked to gain-of-function mutations of Na(v)1...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fischer, Tanya Z., Gilmore, Elaine S., Estacion, Mark, Eastman, Emmanuella, Taylor, Sean, Melanson, Michel, Dib-Hajj, Sulayman D., Waxman, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103031/
https://ncbi.nlm.nih.gov/pubmed/19557861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21678
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados