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CPP-115, a vigabatrin analogue, decreases spasms in the multiple-hit rat model of infantile spasms
OBJECTIVE: Infantile spasms (IS) have poor outcomes and limited treatment options, including vigabatrin, a GABA aminotransferase inactivator. Vigabatrin has been associated with retinal toxicity. A high affinity vigabatrin analogue (CPP-115, Catalyst Pharmaceutical Partners) has shown lower risk of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102583/ https://ncbi.nlm.nih.gov/pubmed/24321005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12424 |
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