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Acquired parvalbumin‐selective interneuronopathy in the multiple‐hit model of infantile spasms: A putative basis for the partial responsiveness to vigabatrin analogs?

West syndrome, an age‐specific epileptic encephalopathy, manifests with infantile spasms (IS) and impaired neurodevelopmental outcomes and epilepsy. The multiple‐hit rat model of IS is a chronic model of IS due to structural etiology, in which spasms respond partially to vigabatrin analogs. Using th...

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Detalhes bibliográficos
Publicado no:Epilepsia Open
Main Authors: Katsarou, Anna‐Maria, Li, Qianyun, Liu, Wei, Moshé, Solomon L., Galanopoulou, Aristea S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293059/
https://ncbi.nlm.nih.gov/pubmed/30564774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/epi4.12280
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