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CPP-115, a vigabatrin analogue, decreases spasms in the multiple-hit rat model of infantile spasms

OBJECTIVE: Infantile spasms (IS) have poor outcomes and limited treatment options, including vigabatrin, a GABA aminotransferase inactivator. Vigabatrin has been associated with retinal toxicity. A high affinity vigabatrin analogue (CPP-115, Catalyst Pharmaceutical Partners) has shown lower risk of...

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Détails bibliographiques
Auteurs principaux: Briggs, Stephen W., Mowrey, Wenzhu, Hall, Charles B., Galanopoulou, Aristea S.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102583/
https://ncbi.nlm.nih.gov/pubmed/24321005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12424
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