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A case report on the efficacy of vigabatrin analogue (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) in a patient with infantile spasms

West Syndrome is characterized by infantile spasms, a hypsarrhythmic electroencephalogram (EEG) pattern, and a poor neurodevelopmental prognosis. First-line treatments include adrenocorticotrophic hormone (ACTH) and vigabatrin, but adverse effects often limit their use. CPP-115 is a high-affinity vi...

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Detalhes bibliográficos
Publicado no:Epilepsy Behav Case Rep
Main Authors: Doumlele, Kyra, Conway, Erin, Hedlund, Julie, Tolete, Patricia, Devinsky, Orrin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024311/
https://ncbi.nlm.nih.gov/pubmed/27668180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebcr.2016.08.002
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