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Regulation of HIF-1 alpha by the proprotein convertases furin and PC7 in human squamous carcinoma cells

Proprotein convertases (PC), a family of serine proteases, process cancer-related substrates such as growth factors, growth factor receptors, cell adhesion molecules, metalloproteinases, etc. HIF-1α is a major transcription factor involved in tumorigenesis by sensing intratumoral hypoxia. Furin (PCS...

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Bibliografische gegevens
Hoofdauteurs: Fu, Jian, Zhang, Jirong, Gong, Yulan, Testa, Courtney Lyons, Klein-Szanto, Andres J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101078/
https://ncbi.nlm.nih.gov/pubmed/24436242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22131
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