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Targeting Proprotein Convertases in Furin-Rich Lung Cancer Cells Results in Decreased In vitro and In vivo Growth

Proprotein convertases (PCs) are serine proteases with an active role in the post-translational processing of numerous inactive proteins to active proteins including many substrates of paramount importance in cancer development and progression. Furin (PCSKC3), a well-studied member of this family, i...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Bassi, Daniel E., Zhang, Jirong, Renner, Catherine, Klein-Szanto, Andres J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166887/
https://ncbi.nlm.nih.gov/pubmed/27584082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22550
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