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Proprotein convertase inhibition: Paralyzing the cell’s master switches
Proprotein convertases are serine proteases responsible for the cleavage and subsequent activation of protein substrates, many of them relevant for the development of an ample variety of diseases. Seven of the PCs, including furin and PACE4, recognize and hydrolyze the C-terminal end of the general...
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| Опубликовано в: : | Biochem Pharmacol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5586041/ https://ncbi.nlm.nih.gov/pubmed/28456517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.04.027 |
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