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Proprotein convertase inhibition: Paralyzing the cell’s master switches

Proprotein convertases are serine proteases responsible for the cleavage and subsequent activation of protein substrates, many of them relevant for the development of an ample variety of diseases. Seven of the PCs, including furin and PACE4, recognize and hydrolyze the C-terminal end of the general...

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Bibliografiska uppgifter
I publikationen:Biochem Pharmacol
Huvudupphovsmän: Klein-Szanto, Andres J, Bassi, Daniel E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586041/
https://ncbi.nlm.nih.gov/pubmed/28456517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.04.027
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