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Regulation of HIF-1 alpha by the proprotein convertases furin and PC7 in human squamous carcinoma cells
Proprotein convertases (PC), a family of serine proteases, process cancer-related substrates such as growth factors, growth factor receptors, cell adhesion molecules, metalloproteinases, etc. HIF-1α is a major transcription factor involved in tumorigenesis by sensing intratumoral hypoxia. Furin (PCS...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101078/ https://ncbi.nlm.nih.gov/pubmed/24436242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22131 |
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