Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature

Background Brain cancer stem-like cells (bCSC) are cancer cells with neural stem cell (NSC)-like properties found in the devastating brain tumor glioblastoma multiforme (GBM). bCSC are proposed a central role in tumor initiation, progression, treatment resistance and relapse and as such present a pr...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kristoffersen, Karina, Nedergaard, Mette Kjølhede, Villingshøj, Mette, Borup, Rehannah, Broholm, Helle, Kjær, Andreas, Poulsen, Hans Skovgaard, Stockhausen, Marie-Thérése
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2014
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100987/
https://ncbi.nlm.nih.gov/pubmed/24755988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28876
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