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Mechanistic Studies of Protein Arginine Deiminase 2: Evidence for a Substrate-Assisted Mechanism
[Image: see text] Citrullination, which is catalyzed by protein arginine deiminases (PADs 1–4 and 6), is a post-translational modification (PTM) that effectively neutralizes the positive charge of a guanidinium group by its replacement with a neutral urea. Given the sequence similarity of PAD2 acros...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American
Chemical Society
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100781/ https://ncbi.nlm.nih.gov/pubmed/24989433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500554b |
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