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ER–Mitochondrial Calcium Flow Underlies Vulnerability of Mechanosensory Hair Cells to Damage

Mechanosensory hair cells are vulnerable to environmental insult, resulting in hearing and balance disorders. We demonstrate that directional compartmental flow of intracellular Ca(2+) underlies death in zebrafish lateral line hair cells after exposure to aminoglycoside antibiotics, a well character...

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Detalhes bibliográficos
Main Authors: Esterberg, Robert, Hailey, Dale W., Rubel, Edwin W, Raible, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099547/
https://ncbi.nlm.nih.gov/pubmed/25031409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0281-14.2014
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