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Fluorescent aminoglycosides reveal intracellular trafficking routes in mechanosensory hair cells

Aminoglycosides (AGs) are broad-spectrum antibiotics that are associated with kidney damage, balance disorders, and permanent hearing loss. This damage occurs primarily by killing of proximal tubule kidney cells and mechanosensory hair cells, though the mechanisms underlying cell death are not clear...

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書目詳細資料
發表在:J Clin Invest
Main Authors: Hailey, Dale W., Esterberg, Robert, Linbo, Tor H., Rubel, Edwin W., Raible, David W.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272180/
https://ncbi.nlm.nih.gov/pubmed/27991862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85052
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