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Fluorescent aminoglycosides reveal intracellular trafficking routes in mechanosensory hair cells

Aminoglycosides (AGs) are broad-spectrum antibiotics that are associated with kidney damage, balance disorders, and permanent hearing loss. This damage occurs primarily by killing of proximal tubule kidney cells and mechanosensory hair cells, though the mechanisms underlying cell death are not clear...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Hailey, Dale W., Esterberg, Robert, Linbo, Tor H., Rubel, Edwin W., Raible, David W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272180/
https://ncbi.nlm.nih.gov/pubmed/27991862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85052
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