Loss of Slc4a1b Chloride/Bicarbonate Exchanger Function Protects Mechanosensory Hair Cells from Aminoglycoside Damage in the Zebrafish Mutant persephone

Mechanosensory hair cell death is a leading cause of hearing and balance disorders in the human population. Hair cells are remarkably sensitive to environmental insults such as excessive noise and exposure to some otherwise therapeutic drugs. However, individual responses to damaging agents can vary...

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Detalhes bibliográficos
Main Authors: Hailey, Dale W., Roberts, Brock, Owens, Kelly N., Stewart, Andrew K., Linbo, Tor, Pujol, Remy, Alper, Seth L., Rubel, Edwin W., Raible, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469417/
https://ncbi.nlm.nih.gov/pubmed/23071446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002971
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